Analytical Standards Guide

Here we'll go through the types of chromatography. But I think it's a good moment to discuss what the different analytical techniques are separated based on.  So, chromatography is a separation based on polarity differences but distillation is something where you separate based on boiling point differences, extraction involves separation based on acidity or basicity and spectroscopy is a way of identifying what kind of compound do you have by looking at what type of light rays it absorbs. If you are thinking about analytical techniques, it's good to know sort of how they work and their general operation but also understand what they separate based on because that can be a very commonly tested topic. Chromatography is all separated based on polarity differences. it separates based on a stationary phase that is rather polar and it has an adsorbent material which is something polar that other things bind with a mobile phase. Which is oftentimes a liquid sometimes a gas but...

  In this article, we will learn method validation fitness for purpose of the analytical method What is analytical method validation? What is the difference between method validation and verification?  Why is the method validation necessary? When should methods be validated or verified?  How should the method be validated? What is analytical method validation? Different international documents have given the method validation definition like as per,  ICH Q2: the analytical procedure is to exhibit that it is suitable for its intended purpose.  United States of pharmacopeia USP: the process by which it's established by laboratory studies that the performance characteristics of the procedure meet the requirement for the intended analytical application  ISO 9000 : confirmation, through the stipulation of objective proof that the demand of specific intended use for application have been fulfilled  ISO/IEC 17025: confirmation, by exami...

What is Chromatography Chromatography is the most commonly applied method for the separation of substance mixtures into single components. This powerful technique is for example used in quality control of drugs, in clinical research, or trace analysis of harmful substances. Chromatography is essential for analytical chemistry around the world.  Symtera Analytics has a comprehensive range of chromatography products from sample preparation to subsequent analysis. Provides scientists with the best solution for each analytical task. In HPLC we provide powerful solutions featuring pre-packed columns with many different selectivities.  Column Chromatography It is a chromatography technique in which separation is carried out in columns. The column is filled with the stationary phase which can either be silica, alumina, or cellulose. The bottom of the column is packed with cotton or glass wool to support the stationary phase. The column preparation is usually carried out...